The Division of Clinical Services is responsible for the supervision of diagnostic, curative, and rehabilitative services. It oversees the provision of health care and supervises the treatment and care given in all the health facilities of MoH. It also collaborates with associations of health professionals to regulate professional conduct. The division is also responsible for the development of policy and guidelines for medical practice, in accordance with MoH Quality Assurance Program. It has three units: Medical Services Unit, Treatment and Care Unit and Licensing Unit.

There has been no National Health Act or Regulation in Eritrea but there are several proclamations on control of drugs, cosmetics and sanitary items, tobacco control, control of private practice and control of female genital mutilation (FGM).

Applications for the registration of a pharmaceutical product submitted to the NMFA for the very first time is considered as a new application. Applications for registration of medicines from new manufacturing facilities not inspected and approved by the NMFA are also expected to submit a site master file (SMF) of the plant in which the product is manufactured. The NMFA may also conduct GMP inspection.